Selank and Semax: Russian Neuropeptides in Cognitive Research

Selank and Semax: Russian Neuropeptides in Cognitive Research

Selank and Semax are synthetic peptides developed in Russia that have been the subject of significant neuroscience research. Both are derived from naturally occurring peptides and have been studied for anxiolytic, nootropic, and neuroprotective properties.

Selank: Anxiolytic Peptide

Selank is a synthetic heptapeptide analogue of the immunomodulatory peptide tuftsin. Research has focused on its effects on GABA receptor modulation, BDNF expression, and the serotonergic system in animal models of anxiety.

Semax: ACTH-Derived Nootropic

Semax (MEHFPGP) is a synthetic analogue of the ACTH 4-7 fragment, extended with Pro-Gly-Pro. It has been studied for its effects on BDNF upregulation, cognitive enhancement, and neuroprotection in various animal models.